Efficacy and Safety of Biomaterials and Antimicrobial Dressings in the Treatment of Diabetic Foot Ulcers: A Systematic Review and Network Meta-Analysis.

ABSTRACT: This systematic review and network meta-analysis is aimed at comparing the efficacy and safety of various wound dressings in the treatment of diabetic foot ulcers, as differences in outcomes among these materials remain unclear. A comprehensive literature search was conducted across major Chinese and international databases up to October 2024, identifying 35 randomized controlled trials involving 2631 patients. Data were extracted and quality-assessed using standardized methods, and a network meta-analysis was performed using appropriate statistical software. The results showed that, compared with traditional dressings, novel biomaterials (e.g., growth factors, amniotic membrane, platelet-rich plasma, and hydrogels) and antimicrobial dressings (e.g., silver ion dressings) combined with bas

SUBMITTER: Zhang J 

PROVIDER: S-EPMC12527605 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature