What should the doctor prescribe-formula diet or antidiabetics? Effectiveness of formula diet-based lifestyle intervention vs. pharmacological antiglycemic therapy on weight loss and HbA1c reduction in type 2 diabetes patients-a systematic review.

ABSTRACT:

Aim

Lifestyle intervention is the basis in type 2 diabetes therapy and leads, combined with formula diet, to substantial improvements in body weight and glycemic control up to diabetes remission. However, pharmacological therapies have also shown promising results. The aim of this systematic review was to compare the effects of large-sized formula diet-based lifestyle interventions vs. pharmacological interventions with glucagon-like peptide 1 receptor agonists (GLP-1 RAs), GLP-1, and glucose-dependent insulinotropic polypeptide (GIP) combinations and sodium glucose cotransporter-2 (SGLT-2) inhibitors on weight and HbA1c reduction in obese type 2 diabetes patients.

Methods

Literature searches were performed using PubMed for articles published until February 5, 2025. Primary

SUBMITTER: Kempf K 

PROVIDER: S-EPMC12527879 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature