A randomized trial of a multimodal lifestyle intervention in cancer survivors.

ABSTRACT:

Introduction

Cancer survivors are often insufficiently physically active, have overweight or obesity, and suboptimal cardiorespiratory fitness. The Small Steps study evaluated a multimodal intervention to address these modifiable risk factors.

Methods

The study randomized 33 cancer survivors to a 10-week multimodal lifestyle intervention (MLI) of exercise training and nutritional counseling or waitlist control (WLC). The co-primary endpoints included body weight and cardiorespiratory fitness capacity; secondary and exploratory endpoints included cardiometabolic and patient-reported measures. Endpoints were analyzed using analysis of covariance.

Results

Participants had a mean (SD) age of 60.3 (14.0) years, 26 (79%) were White, and 18 (55%) were survivors of breast can

SUBMITTER: Brown JC 

PROVIDER: S-EPMC12527883 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature