Association of hemorrhoidal disease with dementia risk: a nationwide cohort study.

ABSTRACT:

Introduction

Research on the association between hemorrhoidal diseases (HDs) and dementia is limited. We explored this relationship in a population-based longitudinal cohort and proposed that individuals with HD may experience a higher incidence of dementia.

Methods

Our study included 381,031 participants drawn from results from the South Korean health-screening cohort database, between 2005 and 2010. HD was identified based on at least two claims using the International Classification of Diseases, Tenth Revision (ICD-10) code I84. We used propensity score matching (PSM) to categorize the participants into two groups based on the presence or treatment of HD. The primary outcome was the incidence of all-cause dementia as determined by two or more claims with ICD-10 codes (F00

SUBMITTER: Woo HG 

PROVIDER: S-EPMC12527892 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature