Primary adrenal lymphoma and its mimics: clinico-radiological differential diagnosis.

ABSTRACT:

Purpose

Primary adrenal lymphoma (PAL) is a rare malignancy with limited data on its characteristics. It can pose diagnostic challenges in differentiating it from other adrenal masses, such as atypical adrenal adenoma (ADE), pheochromocytoma (PCC), and adrenocortical carcinoma (ACC). This study aimed to characterize patients with PAL and compare their clinical, hormonal, and radiological features with other primary adrenal lesions whose computed tomography characteristics do not match those of a typical adenoma.

Methods

This retrospective, single-center study included four patient cohorts: PAL (n=12), ADE (n=31), PCC (n=18), and ACC (n=19), treated at a tertiary care hospital between January 2013 and January 2024.

Results

The histopathological type of all PAL cases wa

SUBMITTER: Klosowski P 

PROVIDER: S-EPMC12527894 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature