Establishment of a value assessment framework for orphan drugs in China: an application of the discrete choice experiment in multicriteria decision analysis.

ABSTRACT:

Objectives

The medical security of orphan drugs faces difficulty in basic medical insurance access in China. Conventional cost-effectiveness analysis in the access process lacks broader value concerns and a value assessment framework is needed. This study aims to construct a multicriteria decision analysis value assessment framework for orphan drugs using the discrete choice experiment method from the perspective of basic medical insurance access in China.

Methods

The attributes and levels of the framework were identified through literature and reports review. An unlabeled discrete choice experiment was employed to determine the relevance and relative importance weight of such attributes for decision-making. Questionnaire was designed based on D-efficient design. Survey was

SUBMITTER: Zhao Z 

PROVIDER: S-EPMC12527902 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature