Lactate to albumin ratio as a prognostic marker for all-cause mortality in patients with venous thromboembolism: a retrospective cohort study.

ABSTRACT:

Background

The lactate to albumin ratio (LAR) may serve as a prognostic marker. This study evaluated its association with clinical outcomes in patients with venous thromboembolism (VTE).

Methods

We performed a retrospective cohort analysis using data from the MIMIC-IV 3.1 database, including 4,181 patients diagnosed with VTE. The primary outcomes were 30-day and 365-day all-cause mortality. Cox proportional hazards models assessed the relationship between LAR and mortality. Restricted cubic spline (RCS) analysis examined the non-linear relationship. Kaplan-Meier (KM) survival curves were generated to compare outcomes across the LAR groups.

Results

Among the 1,992 patients included in the study, mortality rates at 30 and 365 days were 19.58% and 22.69%, respectively. E

SUBMITTER: Huang Y 

PROVIDER: S-EPMC12528031 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature