Effect of β-blockade on measures and reproducibility of heart rate, oxygen uptake and work rate across repeated bouts of short-duration, RPE-regulated exercise.

ABSTRACT:

Purpose

We examined the effect of β-blockade on measures and reproducibility of heart rate (HR), oxygen uptake ( V˙O2 ) and work rate (WR) across repeated bouts of short-duration, RPE-regulated exercise.

Methods

Participants completed an RPE-regulated, interval-based exercise session under control and β-blockade conditions with six 3-min bouts alternating between RPE 13 and RPE 15, separated by 2-min active recovery periods. Participants adjusted treadmill speed/grade to meet the target RPE. Linear mixed effects models assessed the effect β-blockade on exercise responses for each RPE, while intraclass correlation coefficients (ICC) and coefficients of variation (CV) evaluated reproducibility across bouts.

Results

β-Blockade significantly reduced HR (- 36.5 beat min

SUBMITTER: Mitchell BL 

PROVIDER: S-EPMC12528277 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature