Electronic health record interventions to reduce postoperative pregabalin prescribing: a quality improvement initiative.

ABSTRACT:

Purpose

Perioperative gabapentinoids may not provide meaningful analgesia and can have significant adverse events. Our objective was to estimate the association of two electronic health record (EHR) interventions with pregabalin prescribing by the acute pain service (APS) at a multi-site academic health sciences network.

Methods

We conducted a quality improvement initiative using a retrospective observational cohort and a quasi-experimental interrupted time series design. Following a baseline period (19 January 2021-19 January 2022), we introduced a Best Practice Advisory that warned of pregabalin's risks for sedation or respiratory depression. On 19 June 2022, pregabalin was removed as a standard checkbox in the APS orders. The primary outcome was the proportion of patients

SUBMITTER: Tierney S 

PROVIDER: S-EPMC12528309 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature