The intra-oral variation of salivary ions.

ABSTRACT:

Objectives

Dry mouth etiologies, which often present as a combination of hyposalivation and xerostomia, are difficult to differentiate. Employing a combination of a location-based approach in the oral cavity and salivary ion measurement may resolve this differential diagnostic gap. In this light, the aim of this cross-sectional study was to determine the concentrations of salivary sodium, potassium, chloride, phosphate, calcium, ammonium, nitrate, nitrite, fluoride, sulphate and magnesium at 7 intra-oral locations in healthy subjects (N = 30).

Methods

First, sterile foam tipped applicators were selected as the most suitable tool to take saliva samples from these areas. Ion levels were analyzed using a capillary electrophoresis system.

Results

Almost every ion included

SUBMITTER: van Santen JS 

PROVIDER: S-EPMC12528311 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature