Electrochemical skin conductance is associated with peripheral tissue hypoperfusion in septic patients.

ABSTRACT:

Background

Autonomic nervous system (ANS) dysfunction contributes to the pathophysiology of sepsis. However, studies using reliable methods for ANS activity monitoring and evaluating its association with outcomes in sepsis patients are scarce. The Sudoscan^® device offers a non-invasive method to evaluate sympathetic function by measuring electrochemical skin conductance (ESC), but its clinical relevance in sepsis remains unclear. This study aimed to assess autonomic sympathetic activity in septic patients using the Sudoscan^® technology and explore its relationship with peripheral perfusion and outcomes.

Methods

This prospective, observational, single-center study included 97 consecutive adult ICU septic patients without or with shock. Sudoscan^®

SUBMITTER: Joffre J 

PROVIDER: S-EPMC12528571 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature