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Transition probabilities for caries in children receiving silver diamine fluoride: a community-based randomized clinical trial.


ABSTRACT: Silver diamine fluoride (SDF) can effectively prevent and control dental caries, the world's most pervasive noncommunicable disease. This study estimated the transition probabilities for caries in children receiving SDF. The CariedAway study was a community-based cluster-randomized trial of SDF, glass ionomer sealants, and atraumatic restorations conducted in 48 primary schools enrolling predominately low-income minority children in New York, USA. For enrolled children receiving SDF, probabilities were computed for transitions between healthy (sound), diseased (carious), and disease-controlled (arrested) states for 6-year molars using multistate Markov models. Subject-level transition probabilities over one- and two-year periods were then calculated by aggregating states of all 6-year mola

SUBMITTER: Ruff RR 

PROVIDER: S-EPMC12528699 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature