Clinical Value of Various Histological Factors in Cutaneous and Subcutaneous Mast Cell Tumors in 197 Dogs.

ABSTRACT:

Background

Many histological tests have been correlated with outcome in mast cell tumors (MCTs)in dogs, but their statistical independence is uncertain.

Objective

To investigate the clinical value of histological factors in the prognostication of dogs with MCTs.

Animals

One hundred and ninety-seven dogs with 199 histologically diagnosed cutaneous (n = 153) and subcutaneous (n = 43) MCTs treated surgically in primary care practice. All had a commercial prognostic panel performed (Patnaik and Kiupel grade, mitotic count, Ki67, AgNOR, KiAg, c-kit mutation in exons 8 and 11 and KIT localization).

Methods

Retrospective cohort study identifying dogs from searching a commercial laboratory's records (January 2017-August 2020). Follow-up was collected from clinical reco

SUBMITTER: Boyd K 

PROVIDER: S-EPMC12528809 | biostudies-literature | 2025 Nov-Dec

REPOSITORIES: biostudies-literature