Differences in the Fecal Metabolome of Autoimmune Pancreatitis Patients.

ABSTRACT:

Background

Chronic pancreatitis is a risk factor for pancreatic cancer. Autoimmune pancreatitis is a unique form of chronic pancreatitis that is primarily characterized by its immune mediate etiology, clinically resembling pancreatic cancer, yet uniquely responsive to steroid treatment.

Objective

Early and accurate diagnosis of autoimmune pancreatitis is vital for effective treatment and patient prognosis, for which new diagnostic tools are urgently required. Gut microbiota dysbiosis has been identified to correlate with the development of pancreatic diseases, which provides new opportunities for the discovery of disease biomarkers.

Methods

We utilized a mass spectrometric global metabolomics investigation of patient autoimmune pancreatitis and chronic pancreatitis fe

SUBMITTER: Dovhalyuk V 

PROVIDER: S-EPMC12529019 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature