Chiral tether-guided selective synthesis of <i>D</i> _<i>n</i> -symmetric chiral conjugated nanorings.

ABSTRACT: Chiral conjugated nanorings with D _n symmetry exhibit extraordinary circularly polarized luminescence (CPL) properties due to their unique cylindrical helical conjugated system. However, their synthesis faces challenges such as numerous atropisomers and tedious separation and chiral resolution processes, which severely hinder their development. In this work, we report a chiral tether-guided synthesis strategy. By introducing a strained planar chiral alkyl chain tether into the fused-ring building unit of the nanoring, the energy differences between the various atropisomers of the nanoring are significantly increased. This guides the formation of the thermodynamically most stable D _n -symmetric isomer during synthesis, thus greatly enhancing

SUBMITTER: An T 

PROVIDER: S-EPMC12529082 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature