Isolation and Characterization of Four New Coliphages against Extra Intestinal Pathogenic <i>Escherichia coli</i> Isolates Recovered from Cystic Fibrosis Patients.

ABSTRACT: Cystic fibrosis (CF) is a common genetic disorder that significantly reduces life expectancy, particularly among Caucasians. It is caused by mutations in the CFTR protein, leading to thick mucus secretions that encourage microbial colonization, particularly in the lungs. While Pseudomonas aeruginosa and Staphylococcus aureus are well-established contributors to CF lung infections, recent research highlights a more diverse range of pathogens, including Escherichia coli, which is not typically considered a respiratory pathogen. In this study, we identified and characterized four new bacteriophages with lytic properties specifically targeting multidrug-resistant Extraintestinal Pathogenic E. coli strains isolated from CF patients. Phages were isolated from wastewat

SUBMITTER: Garcia-Gonzalez G 

PROVIDER: S-EPMC12529148 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature