COVID-19 Booster Vaccine Messaging in Emergency Departments: A Cluster Randomized Clinical Trial.

ABSTRACT:

Importance

Patient uptake of updated COVID-19 vaccines is crucial for reducing severe outcomes, yet national uptake remains low.

Objective

To determine if tailored messaging or simple inquiry about vaccine acceptance increases 30-day uptake of updated COVID-19 vaccines among emergency department (ED) patients.

Design, setting, and participants

This 3-arm, cluster randomized clinical trial conducted from January 29 to June 18, 2024, enrolled adult ED patients who had not received a COVID-19 vaccine in the prior 6 months across 6 EDs in San Francisco, California; Philadelphia, Pennsylvania; Houston, Texas; and Durham, North Carolina.

Interventions

Intervention M involved tailored messaging about updated COVID-19 vaccines and inquiry about vaccine acceptance. Inte

SUBMITTER: Molina MF 

PROVIDER: S-EPMC12529187 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature