Design and synthesis of enantiopure NHC-silver(i) and NHC-gold(i) complexes with anticancer, anti-inflammatory and antioxidant properties.

ABSTRACT: So far, several interesting reports dealing with N-heterocyclic carbene (NHC) complexes bearing silver and gold have been published, highlighting their versatility in several research fields and their various applications as well. However, most of the reported NHC complexes have been synthetically obtained and studied as racemates, whereas less is still known about the properties of enantiopure complexes. Aiming at contributing to fill this gap, herein a new series of enantiopure NHC complexes of silver(i) and gold(i) bearing an imidazole derivative, opportunely substituted, with one or two asymmetric carbons has been synthesized. These complexes have been characterized by ¹H and ¹³C NMR, mass spectrometry, and elemental analysis and studied for their anticance

SUBMITTER: Iacopetta D 

PROVIDER: S-EPMC12529337 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature