Chitosan-ZnO Nanocomposite Nanocatalyst for the Synthesis of 12-Azatetraphene-8-one and 7‑Azatetraphene-11-one Derivatives via Unsymmetrical Hantzsch-Like Reactions.

ABSTRACT: The chitosan-ZnO nanocomposite nanocatalyst was employed as a robust, recyclable, and environmentally benign catalyst to efficiently facilitate the regioselective Hantzsch-like multicomponent reactions involving one-mole equivalent of an aldehyde, 1(2)-naphthyl amine, and dimedone. The reactions afforded tetrahydrobenzo-[c]-acridin-8-one and tetrahydrobenzo-[a]-acridin-11-one derivatives. The formed structures were assigned based on 2D-NMR. The same products have been obtained from the reaction of cyclic enaminones with aldehydes in acetic acid.

SUBMITTER: Mohamed HH 

PROVIDER: S-EPMC12529390 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature