Interplay of population mobility, healthcare resources, and spatiotemporal clustering: epidemiology and prevention strategies for HIV among blood donors in Zhejiang, China.

ABSTRACT:

Background

This study leverages Zhejiang Province's HIV-confirmed positive blood donor database (2017-2024), integrating multidimensional data including demographic, serological, geospatial, and policy indicators to systematically analyze infection risk factors, screening marker characteristics, spatiotemporal distribution patterns, migration impacts, and the regulatory effects of healthcare resource allocation and government investment on donor HIV positivity.

Methods

5,204,965 voluntary donors underwent nucleic acid/serological testing. Multivariate logistic regression, spatiotemporal scan statistics (SaTScan), estimated annual percentage change (EAPC) modeling, and correlation analyses were applied. Healthcare capacity was evaluated via principal component analysis (PCA)

SUBMITTER: Wu D 

PROVIDER: S-EPMC12529598 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature