Gout flares following acute stroke: a single-center cohort and a systematic review/meta-analysis.

ABSTRACT:

Background

With the global prevalence of hyperuricemia and gout rising, accumulating evidence has linked acute gout flares to a transient rise in major adverse cardiovascular events, including myocardial infarction and stroke. However, the reverse association, whether acute stroke is associated with an increased incidence of gout flares, has been inadequately investigated. The aim of this single-center cohort study, coupled with a systematic review and meta-analysis, was to evaluate the incidence and characteristics of gout flares in the early post-stroke period.

Methods

A systematic review and meta-analysis of published studies was conducted, incorporating data from a cohort of acute stroke patients admitted to a tertiary care stroke center. Eligible studies reported in-hos

SUBMITTER: Panagiotopoulos E 

PROVIDER: S-EPMC12529815 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature