Global burden of dengue from 1990 to 2021: a systematic analysis from the Global Burden of Disease study 2021.

ABSTRACT:

Background

Dengue fever remains a major global public health challenge, with increasing incidence and burden over recent decades. Global warming, urbanization, and increased international travel have fueled the global spread of dengue. Despite escalating global concern, recent and consistent estimates of the global dengue burden remain limited. This study aimed to quantify the shifting trends of dengue fever.

Methods

We analyzed the 2021 Global Burden of Disease (GBD) dataset to assess dengue fever's incidence, prevalence, mortality, and disability-adjusted life years (DALYs) from 1990 to 2021 across 204 countries/regions. Data were stratified by age, sex, and socio-demographic index (SDI) using age-standardized rates, and time-trend analysis was conducted with general linea

SUBMITTER: Zheng J 

PROVIDER: S-EPMC12529819 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature