Omics-based profiling and therapeutic potential of natural components in pan-Shennongjia medicinal herbs.

ABSTRACT: The pan-Shennongjia region represents a globally significant biodiversity hotspot characterized by high species diversity and endemism. While its rich medicinal resources have long been recognized, the systematic characterization of their natural components and therapeutic potential remains underexplored. Here, we integrated 405 representative biological species from the pan-Shennongjia region, corresponding to 323 traditional Chinese medicine materials, into a Chinese genus-species level phylogenetic tree. We identified clade-specific species enrichments at the family level within this region. Notably, case studies of Chrysanthemum indicum var. aromaticum and Dendrobium flexicaule and Chrysanthemum indicum var. aromaticum revealed specificized accumulations of polysaccharides and volatile

SUBMITTER: Song J 

PROVIDER: S-EPMC12529840 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature