The association between iron deficiency and muscle mass/strength in patients undergoing maintenance hemodialysis.

ABSTRACT:

Background

Patients with end-stage renal disease (ESRD) are at high risk of losing muscle mass and strength, especially those undergoing maintenance hemodialysis (MHD). Iron deficiency (ID) may exacerbate this condition, however, its relationship with muscle mass/strength remains largely unclear. Therefore, we aim to investigate the association between ID status and muscle mass/strength in Chinese patients undergoing hemodialysis.

Methods

This cross-sectional study was conducted at a hemodialysis center in southwest China from September to December 2022. Iron status was assessed by plasma ferritin and transferrin saturation (TSAT). Muscle strength was measured by handgrip strength (HGS), and muscle mass was evaluated using the appendicular skeletal muscle index (ASMI). Linea

SUBMITTER: Liu Y 

PROVIDER: S-EPMC12529934 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature