Impact of Blood Pressure Self-Management on Vascular Remodeling After Hypertensive Pregnancy.

ABSTRACT:

Background

Hypertensive pregnancy disorders are associated with long-term adverse cardiac and vascular remodeling post index pregnancy. The POP-HT trial (Physician Optimised Postpartum Hypertension Treatment) demonstrated that improved puerperal blood pressure control leads to reduced blood pressure and beneficial cardiac remodeling during the first year postpartum. This study describes the impact on postpartum vascular remodeling.

Methods

A prospective, randomized, open-label, blinded end point trial in a single UK hospital where 220 women were assigned 1:1 to intervention (self-management via physician-guided antihypertensive titration) or control (usual postnatal care via primary care doctor±midwife). Eligible participants were ≥18 years, with preeclampsia or gestational

SUBMITTER: Kitt J 

PROVIDER: S-EPMC12529981 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature