Linker desymmetrisation unlocks new topologies, defective clusters, and catalytic activity in zirconium- and rare-earth metal-organic frameworks.

ABSTRACT: Metal-organic frameworks (MOFs) based on highly connected nets continue to expand the landscape of reticular chemistry, with zirconium (Zr) and rare-earth (RE) clusters offering ideal nodes for the construction of robust and structurally diverse materials. While desymmetrisation of tetratopic linkers has recently emerged as a promising approach to accessing new framework topologies, the underlying principles governing cluster connectivity remain poorly understood. Here, we systematically investigate the effect of linker desymmetrisation on the assembly of Zr- and RE-MOFs. A literature survey of planar tetratopic linkers revealed that geometric parameters such as height-to-width ratio and torsion angles play a key role in dictating cluster connectivity. Guided by these insights, we designed

SUBMITTER: Ortin-Rubio B 

PROVIDER: S-EPMC12530136 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature