Comparison of Spectrum Coverage Score-based Antimicrobial Consumption in Acute Care Hospitals Over Eight Years: A Multicentric Study.

ABSTRACT:

Background

Progress in antimicrobial stewardship programs has introduced new means of assessing antimicrobial use. Days of antibiotic spectrum coverage (DASC) incorporate spectrum data into traditional metrics, such as days of therapy (DOT). This study evaluated DASC across 12 hospitals to assess antimicrobial consumption and the streamlining process.

Methods

Data on antimicrobial consumption were collected from 12 hospitals in three regions from April 2016 to March 2024. Trends in streamlining (DASC/DOT) were assessed using linear regression. Spearman's rank-order correlation was used to test for any correlation between DASC/DOT and DOT per 1000 patient-days (PD). Hospital features, including intensive care unit (ICU) capacity and transplant services, were also assessed.

SUBMITTER: Honda H 

PROVIDER: S-EPMC12530326 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature