The Influence of the Introduction of Fetal Anomaly Scans on Pregnancy Terminations in Cases of Upper Limb Anomalies: A Retrospective Cohort Study From 2000 to 2023.

ABSTRACT:

Objective

To examine the association between the introduction of the fetal anomaly scans in the Netherlands and termination of pregnancy (TOP) in cases of prenatally detected upper limb anomalies.

Methods

We conducted a retrospective study among prenatally detected upper limb anomalies between 2000 and 2023. Anomalies were categorized as reduction defects, syndactyly, or polydactyly, and classified as isolated or non-isolated. We analyzed TOP rates across three periods (2000-2006, 2007-August 2021, September 2021-2023), including an interrupted time series (ITS) analysis to assess the impact of introducing second- and first-trimester anomaly scans (STAS, FTAS).

Results

We included 300 pregnancies, of which 133 (44.3%) were isolated. Overall TOP rates did not differ si

SUBMITTER: Arduc A 

PROVIDER: S-EPMC12530345 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature