A Practical Prenatal Ultrasound Classification System for Lower Limb Anomalies-PRELLIM Classification.

ABSTRACT:

Objective

To address the current lack of a prenatal classification system for fetal lower limb anomalies, we developed and evaluated the PRELLIM (PREnatal Lower LIMb impairment) classification.

Method

A systematic literature review was conducted to identify existing classifications. Based on sonographic features, we developed the PRELLIM classification and applied it to a retrospective cohort of fetuses with isolated lower limb anomalies assessed between 2007 and 2024 at Amsterdam UMC's fetal medicine unit.

Results

No standardized prenatal classification system for lower limb anomalies was found. PRELLIM distinguishes isolated and non-isolated anomalies and categorizes them into clinically relevant subgroups (absent/short, duplication, fusion, contracture, bowing and

SUBMITTER: Arduc A 

PROVIDER: S-EPMC12530349 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature