Case report of a transcatheter pulmonic valve-in-valve replacement through a bioprosthetic tricuspid valve in a patient with carcinoid heart disease.

ABSTRACT:

Background

Carcinoid heart disease (CHD) is a paraneoplastic syndrome that occurs in patients with metastatic neuroendocrine tumours (NETs), often resulting in right-sided valvular dysfunction and heart failure. Surgical valve replacement is the main treatment for CHD with valvular involvement, though many patients will eventually develop prosthetic valve degeneration.

Case summary

We present a case of a 70-year-old female with metastatic NET, complicated by CHD status post-surgical tricuspid and pulmonary valve replacement who presented with dyspnoea. She was found to have worsening right-sided heart failure in the setting of severe bioprosthetic pulmonic valve regurgitation. Given the patient's metastatic NET, prior sternotomy, and overall frailty, it was felt that surgica

SUBMITTER: Lyons R 

PROVIDER: S-EPMC12530353 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature