Left bundle branch pacing in patients with structural heart disease: personalizing cardiac resynchronization therapy.

ABSTRACT: Biventricular pacing remains the cornerstone of cardiac resynchronization therapy (CRT) in patients with heart failure, with well-established benefits. Left bundle branch pacing (LBBP) offers a physiologic alternative by engaging the native conduction system to restore synchrony and has generated significant enthusiasm. However, the growing adoption of LBBP should be tempered by recognition that a one-size-fits-all approach may not address the underlying substrate, particularly in those with intraventricular conduction delay. While a less-than-optimal LBBP implant may be sufficient in bradycardia patients, its adequacy in heart failure patients, who may require more precise consideration of conduction disease, remains uncertain. This review gives a comprehensive framework for integrating L

SUBMITTER: Joza J 

PROVIDER: S-EPMC12530354 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature