A heat stress-responsive epigenome defines the dynamic 3D chromatin structure in Chinese cabbage.

ABSTRACT: Plants have evolved genome plasticity to adapt to fluctuating environments. However, how environmental cues induce dynamic chromatin remodeling in plants remains largely unclear. Here, we report a close relationship between the epigenome and the 3D chromatin structure in the plant response to heat stress. Through Hi-C, whole-genome bisulfite sequencing, and transcriptome analyses in Chinese cabbage (Brassica rapa), we found that heat stress rapidly induces chromatin compaction and aggregation predominantly in centromeric and telomeric regions. Heat stress also markedly altered A/B compartment transitions and the number and length of TAD-like domains and loops, as well as genome-wide DNA methylation profiles that were linked to the maintenance of chromatin stability and transcription levels

SUBMITTER: Yang Q 

PROVIDER: S-EPMC12530355 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature