Cohort of allergic rhinitis evaluation of effectiveness and safety of herbal medicine (CARE-HM): protocol for the clinic-based multicentre Korean Medicine Registry.

ABSTRACT:

Background

Allergic rhinitis (AR) is a common chronic inflammatory condition that significantly impairs quality of life (QoL) through symptoms such as nasal congestion, rhinorrhoea, sneezing and itching. Conventional treatments often show limitations, prompting interest in complementary therapies like herbal medicine (HM). HM is widely used in East Asian countries and has demonstrated potential in modulating immune responses and reducing AR symptoms. In Korea, a government pilot project expanded in 2024 to include AR under limited insurance coverage for HM, highlighting the need for robust clinical evidence on its safety and effectiveness.

Methods and analysis

This study is a multicentre, prospective registry conducted in 21 Korean Medicine (KM) clinics across Republic of Ko

SUBMITTER: Kim SD 

PROVIDER: S-EPMC12530414 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature