Integration of mathematical modeling and economics approaches to evaluate strategies for control of Salmonella Dublin in a heifer-raising operation.

ABSTRACT: Salmonella Dublin infections in heifer-raising operations (HROs) cause animal health and economic losses for these operations and represent a pathogen source for dairy farms obtaining replacement heifers from HROs. To improve control of S. Dublin, we (i) developed a mathematical model of S. Dublin transmission on a HRO, (ii) evaluated the vaccine effectiveness and cleaning improvements for controlling the infection, and (iii) evaluated the influence of infection and control strategies on the HRO's operating income. We developed a modified Susceptible-Infected-Recovered-Susceptible model of S. Dublin spread in a batch-stocking HRO post-introduction of an index case, with stochasticity introduced through Monte Carlo simulations. Epidemiological outcomes (S. Dublin-induced deaths and abortion

SUBMITTER: Llanos-Soto S 

PROVIDER: S-EPMC12530588 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature