Intraoperative Hypotension and Major Adverse Cardiac Events Among Older Adult Patients Undergoing Noncardiac Surgery: Retrospective Cohort Study.

ABSTRACT:

Background

Intraoperative hypotension (IOH) is an important risk factor for major adverse cardiac events (MACE) in patients undergoing noncardiac surgery. However, the IOH threshold in older adult patients remains controversial.

Objective

This study aimed to explore an appropriate IOH threshold in older adult patients to decrease the risk of MACE.

Methods

This study involved older adult patients undergoing noncardiac surgery (age ≥65 y) from January 2012 to August 2019 in the Chinese People's Liberation Army General Hospital (PLAGH; 35,262 patients) and Shanghai Changhai Hospital from January 2024 to December 2024 (13,418 patients). Univariate moving-average plots and multivariate restricted cubic splines were used to determine the IOH thresholds associated with an in

SUBMITTER: Zhang K 

PROVIDER: S-EPMC12530642 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature