Impact of Pulmonary Vein Isolation on Atrial Fibrillation Organisation: Correlation of Intracardiac and Surface Electrocardiogram Measures.

ABSTRACT:

Introduction

Electrical activity in atrial fibrillation (AF) ranges from organized focal drivers to multiple wavelet re-entry. Understanding the effect of pulmonary vein isolation (PVI) on AF organization is clinically important, as it may optimize treatment strategies and outcomes. This study investigates the impact of PVI on AF organization and explores whether ventricular response regularity, measured from surface electrocardiograms (ECGs), reflects AF dynamics and electrophenotype.

Methods

Patients undergoing first-time PVI at Imperial College Healthcare NHS Trust between 2014 and 2022 were assessed pre- and post-PVI. AF organization was quantified using Shannon entropy (ShEn) and Sample entropy (SampEn) from coronary sinus (CS) electrograms. Ventricular response regular

SUBMITTER: Ahsan N 

PROVIDER: S-EPMC12530675 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature