Recent Advances in Injectable Hydrogel Biotherapeutics for Regenerative Dental Medicine.

ABSTRACT: Dental caries and periodontitis continue to be significant oral health challenges. Traditional therapies typically manage infection and inflammation but seldom restore lost tissue. In this way, injectable hydrogels have emerged as versatile biomaterials that adapt to the complex anatomy of the dentin-pulp complex and periodontal lesions. Generally speaking, by incorporating antimicrobial, anti-inflammatory, and pro-regenerative cues, these hydrogels support localized disinfection, promote angiogenesis, and foster tissue regeneration. More specifically, recent advances in functionalizing hydrogels with growth factors, bioactive compounds, and dentin matrix components have effectively modulated inflammatory responses, stimulated host cell activity, and facilitated the formation of hard and s

SUBMITTER: Dal-Fabbro R 

PROVIDER: S-EPMC12530706 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature