Effects of Cataract Surgery on Melatonin Secretion in Adults 60 Years and Older: A Randomized Clinical Trial.

ABSTRACT:

Importance

Cataract surgery, which increases perception of light, may increase melatonin secretion. Melatonin secretion has been associated with depression, diabetes, cognitive impairment, and breast cancer. To date, no evidence from a randomized clinical trial exists to support this cataract surgery hypothesis.

Objective

To determine whether cataract surgery modifies the melatonin secretion at 3 months after cataract surgery in 169 adult patients.

Design, setting, and participants

A parallel-group randomized clinical trial was conducted at a single referral center from July 1, 2014, to June 30, 2017. Data were analyzed from January 1, 2018, to March 31, 2019. Patients were aged 60 years or older, had no history of cataract surgery, and had cataracts with grade 2 or h

SUBMITTER: Nishi T 

PROVIDER: S-EPMC12530708 | biostudies-literature | 2020 Apr

REPOSITORIES: biostudies-literature