The Prognostic Interplay of Heart Failure and Chronic Kidney Disease in Atrial Fibrillation - Focus on Cardiorenal Outcomes.

ABSTRACT:

Background

HF and CKD create a mutually reinforcing cycle, escalating disease development, and increasing morbidity and mortality rates. Both are common comorbidities promoting AF and contributing to heightened symptom burden and poorer outcomes in AF. Here our aim was to investigate the relationship of heart failure (HF) and chronic kidney disease (CKD) with cardiorenal outcomes in patients with atrial fibrillation (AF).

Methods

Patients with AF, treated at a tertiary centre between 01/2005 and 07/2019 were included. The primary endpoint was a composite of cardiovascular (CV) death and hospitalization for HF (HHF). Secondary outcomes were the individual components of the primary endpoint, all-cause death, renal death, and dialysis.

Results

We included a total of 7,41

SUBMITTER: Baumer U 

PROVIDER: S-EPMC12530782 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature