Hemolytic Disease of the Fetus and Newborn in an Integrated Health Care System.

ABSTRACT: Hemolytic disease of the fetus and newborn (HDFN) is associated with significant infant morbidity and mortality. Characteristics of pregnancies impacted by HDFN are not well understood. Therefore, this study examines maternal and infant characteristics based on HDFN status in a large, integrated health care system in the United States.This was a population-based, retrospective cohort study of 464,711 pregnancies that received care at Kaiser Permanente Southern California (KPSC) hospitals from January 2008 to June 2022. HDFN cases were ascertained using a validated algorithm of structured and unstructured data elements. HDFN due to ABO alloimmunization alone was excluded. Adjusted odds ratios (aORs) derived from logistic regression were used to describe the association between maternal and

SUBMITTER: Fassett MJ 

PROVIDER: S-EPMC12530894 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature