Distinct Imaging Features of Peripheral Nerve Sheath Tumours in <i>NF2</i>-Related Schwannomatosis: A Case Report.

ABSTRACT:

Introduction

Peripheral nerve sheath tumours (PNST) are an important feature of the NF2-related schwannomatosis. These constitute primarily schwannomas which are characterized as nodular, solitary benign tumours of single fascicles. We here describe a pronounced, extensive, multifascicular enlargement of the right ulnar nerve and bilateral brachial plexus in a teenage patient with NF2-related schwannomatosis. Neither their imaging nor the clinical characterization were consistent with classic schwannomas.

Methods

Within a multimodal work-up, detailed and standardized high-resolution nerve ultrasound was correlated to clinical, electroneurographic, and MRI findings. Follow-up data over 2 years were provided.

Results

The clinical presentation of a slowly p

SUBMITTER: Hanna K 

PROVIDER: S-EPMC12530925 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature