Efficacy and influencing factors of modified electroconvulsive therapy for schizophrenia: a real-world retrospective observational study.

ABSTRACT:

Background

Schizophrenia (SCZ) is a chronic and disabling psychiatric disorder. Modified Electroconvulsive Therapy (MECT), which involves electrical stimulation under general anaesthesia and muscle relaxation, is widely used to treat SCZ. Despite its rapid onset and robust therapeutic effect, the efficacy of MECT varies significantly between individuals. This study aimed to evaluate the clinical effectiveness of MECT in patients with SCZ and identify its influencing factors, with the goal of informing personalised treatment strategies.

Methods

This retrospective observational study included 237 inpatients with SCZ who received a full course of MECT at the Fourth People's Hospital of Nantong between January 2023 and December 2024. Treatment response was evaluated using the Po

SUBMITTER: Wang Z 

PROVIDER: S-EPMC12531135 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature