Comparing the Effectiveness and Safety of Remdesivir and Molnupiravir in COVID-19: A Systematic Review and Meta-Analysis.

ABSTRACT:

Background

Remdesivir and molnupiravir have been approved and are being used as viable treatment options for patients with coronavirus disease 2019 (COVID-19). This systematic review and meta-analysis sought to evaluate and compare the safety and effectiveness of these two antiviral drugs in the treatment of COVID-19.

Methods

An extensive search was conducted across several databases, including Web of Science, PubMed, the Cochrane Library, and medRxiv, up to July 1, 2024. To evaluate the risk of bias, a standardized bias assessment tool was used. Data from the selected studies were analyzed using Comprehensive Meta-Analysis software.

Results

The analysis included data from 10 studies, encompassing a total of 5766 patients. According to the meta-analysis, remdesivir an

SUBMITTER: Moghadam SHP 

PROVIDER: S-EPMC12531351 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature