Exploring upper airway and laryngeal resistance to noninvasive ventilation in healthy awake adults.

ABSTRACT: The interaction between anatomical structures, pressure, and airflow impacts the airway resistance. The airflow during noninvasive ventilation (NIV) relies on the upper airway and laryngeal patency. This study aimed to quantify the airflow resistance at these levels during NIV. In this cross-sectional study examining 10 healthy, awake adults, we established a NIV setup incorporating a continuous video-recorded transnasal laryngoscopy and simultaneous airway pressure measurement using a transducer positioned above and below the vocal folds. Airflow and mask pressure were recorded by a pneumotachograph at the mask. NIV was delivered with inspiratory positive pressure (IPAP)/expiratory positive pressure (EPAP) set to 10/4 and 15/4 cmH₂O. Upper airway (R_uaw) and translary

SUBMITTER: Brekka AK 

PROVIDER: S-EPMC12531353 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature