Impact of multiparametric MRI and prostate biopsies on anxiety and quality of life in men with suspected prostate cancer.

ABSTRACT:

Objectives

To study the impact of the new MRI pathway and conventional transrectal ultrasound-guided systematic biopsies (TRUSGB) on anxiety and HRQoL in men with suspected PCa.

Materials and methods

A secondary analysis was performed of a randomized clinical trial including 626 biopsy-naïve patients. All patients underwent mpMRI and TRUSGB. Men with suspicious lesions on mpMRI underwent MRGB prior to TRUSGB. Anxiety was measured by State-Trait Anxiety Inventory-Trait Scale (STAI-6), completed at baseline, directly after mpMRI, MRGB, TRUSGB, after two/three weeks, and six months. HRQoL was measured by EuroQol (EQ-5D-5L), European Organization for Research and Treatment of Cancer Quality of Life Questionnaire Core 30 (QLQ-C30) and Prostate Cancer Module (QLQ-PR25). Outcomes w

SUBMITTER: Hamoen EHJ 

PROVIDER: S-EPMC12531450 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature