Comparative effects of enteral nutrition strategies on nutritional indices, inflammatory factors, and clinical outcomes in patients with severe traumatic brain injury.

ABSTRACT:

Objective

To evaluate the effects of different enteral nutrition (EN) strategies on nutritional status, inflammatory factors, immune markers, coagulation function, and clinical outcomes in patients with severe traumatic brain injury (sTBI).

Methods

A retrospective analysis was conducted on 121 sTBI patients treated at Yiwu Central Hospital between January 2023 and January 2025. Among them, 58 received early EN alone (control group) and 63 received early EN with probiotics (study group). Pre- and post-treatment comparisons between the two groups included: nutritional indices (total protein [TP], albumin [ALB], and prealbumin [PA]), inflammatory factors (interleukin-6 [IL-6], C-reactive protein [CRP], and tumor necrosis factor-α [TNF-α]), immune-related markers (immunoglobulin

SUBMITTER: Chen H 

PROVIDER: S-EPMC12531519 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature