Visual acuity, amblyopia and refractive error in preterm children with and without retinopathy of prematurity - Results from the Gutenberg Prematurity Study Young (GPSY).

ABSTRACT:

Purpose

This study aims to assess visual outcomes in children born preterm, stratified by gestational age, hypo- and hypertrophy, and the presence of retinopathy of prematurity (ROP) and its treatment.

Methods

This is a prospective observational cohort study (n = 949, 1889 eyes) assessing visual acuity, amblyopia, refractive error, and lens opacifications in a large sample of children born preterm and full-term aged 4-17 years. Covariates included gestational age, birth weight percentile, ROP status and treatment, maternal smoking, placental insufficiency, preeclampsia, breastfeeding, and perinatal adverse events with an adjustment for sex and age. Logistic regression analysis was conducted to evaluate associations.

Results

Amblyopia prevalence was mainly associated w

SUBMITTER: Fieß A 

PROVIDER: S-EPMC12531598 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature