Effectiveness and safety of repeated photodynamic therapy in recurrent central serous chorioretinopathy.

ABSTRACT:

Purpose

To evaluate anatomical and functional outcomes after a second photodynamic therapy (PDT) in patients with central serous chorioretinopathy (CSC), who had a recurrence of subretinal fluid (SRF) after a previously successful PDT.

Methods

In this multicentre retrospective cohort study, we included patients with CSC who underwent a second PDT because of a recurrence of SRF after an effective first PDT with complete SRF resolution. Diagnosis of CSC was based on multimodal imaging. We evaluated the complete resolution rate of SRF after a second PDT with reduced settings. Also, visual acuity (VA), subfoveal ellipsoid zone (EZ) and subfoveal external limiting membrane (ELM) integrity before and after the first and the second PDT were studied.

Results

A total of 88 pat

SUBMITTER: van den Tillaart FM 

PROVIDER: S-EPMC12531609 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature