Revisiting motor inhibition in individuals with functional paralysis and spinal cord injury.

ABSTRACT: Functional paralysis (FP), a subtype of functional neurological disorder (FND), is characterized by symptoms of paralysis without clinically evident damage to the nervous system. Previous research has reported impaired inhibitory control in FND, such as weaker inhibition and slower response latencies, yet the underlying neural correlates remain unclear. Moreover, it is unknown whether such neural correlates depend on the symptoms or are a specific trait of the disorder. To address this gap, we compared individuals with chronic FP, healthy controls (HCs) and individuals with spinal cord injury (SCI), who present a similar symptom phenotype but differ in the cause of their condition, hence provided the opportunity to disentangle disorder-specific from symptom-specific patterns of neural acti

SUBMITTER: Vallesi V 

PROVIDER: S-EPMC12531627 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature