Plasma transfusion practice: A five-year audit of plasma transfusion at 23 hospitals.

ABSTRACT:

Background

There is limited high-quality evidence to guide plasma transfusion, and plasma transfusion practices remain variable.

Study design and methods

This is a retrospective cohort study that included adult medical and intensive care unit (ICU) inpatients (age ≥ 18 years) admitted to 23 hospitals in Canada between January 1, 2017, and December 31, 2022, when both whole blood derived (~290 mL) and apheresis plasma (~250 mL) were available for transfusion. Nine additional hospital sites with missing plasma data or coagulation testing were excluded. Data collected included patient demographics, most responsible diagnoses, procedures, laboratory tests, transfusion information, and physician characteristics.

Results

Among 950,740 included hospital admissions at 23 hosp

SUBMITTER: Gabarin N 

PROVIDER: S-EPMC12531937 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature